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KMID : 0882419930440050689
Korean Journal of Medicine
1993 Volume.44 No. 5 p.689 ~ p.696
A Case of Pancreatic Somatostatinoma with Metastasis to the Liver and Uterus
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Abstract
omatostatinoma, a rare endocrine tumor, is characterized by diarrhea, steatorrhea,
diabetes, and cholelithiasis due to excessive production of somatostatin.
We report a case of a 32-year-old woman with pancreatic somatostatinoma that
metastasized to the liver and uterus. The patient first presented with jaundice and diarrhea,
and subsequently ascites and vaginal bleeding. The diagnosis was made by the pathologic
examination, immunohistochemistry, and elevated plasma level of somatostain. The patient
was transiently improved with recombinant r-interferon therapy.
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